反应详情

温度

50 °C

A suspension of (2E)-1,2,6,7-tetrahydro-8H-cyclopenta[b]furo[3,2-d]pyridin-8-ylideneacetonitrile (10.0 mg, 0.054 mmol) and Raney cobalt (100 mg) in 2M ammonia/ethanol (1 mL) was stirred at 50° C. for 3 hr under a hydrogen atmosphere. The catalyst was filtered through celite, and the filtrate was concentrated under reduced pressure to give the title compound (10.0 mg, yield 99%).

1. filtrationThe catalyst was filtered through celite
2. concentrationthe filtrate was concentrated under reduced pressure