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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2390146Generated: October 29, 2026

tert-Butyl bromoacetate → Tert-butyl (2-bromo-4-trifluoromethylphenoxy)acetate

https://huagongshe.com/reaction/2390146

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl bromoacetateHCID 79177—
Reactant2-Bromo-4-(trifluoromethyl)phenolHCID 2761168—
Reactanttert-Butyl (2-bromo-4-chlorophenoxy)acetateHCID 49766393—
ProductTert-butyl (2-bromo-4-trifluoromethylphenoxy)acetateHCID 58297405—

Reaction Steps

Following the general method as outlined in Intermediate 1, starting from 2-bromo-4-(trifluoromethyl)phenol and tert-butyl bromoacetate (Aldrich), the title compound was obtained as a dark orange sticky solid in quantitative yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273769B2
Source datasetuspto-grants-2012_09
ORD IDord-7c743510e981458c86050c046a9f8794
Source noteuspto-grants-2012_09