Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Bromopyridine-4-carboxaldehyde → 3-Bromo-4-(prop-1-en-1-yl)pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Bromopyridine-4-carboxaldehyde | HCID 2762997 | — |
| 반응물 | 3-Bromo-4-(hex-1-en-1-yl)pyridine | HCID 67008079 | — |
| 촉매 | Phosphonium, ethyltriphenyl-, bromide (1:1) | HCID 73727 | — |
| 생성물 | 3-Bromo-4-(prop-1-en-1-yl)pyridine | HCID 67008087 | — |
반응 단계
Following the general method as outlined in Intermediate 12, starting from 3-bromo-4-pyridinecarboxaldehyde (Aldrich) and ethyltriphenylphosphonium bromide, the title compound (mixture of cis and trans isomers) was obtained as a colorless liquid after purification by flash column chromatography, eluting with cyclohexane containing increasing amounts of EtOAc.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08273769B2 |
| 출처 데이터셋 | uspto-grants-2012_09 |
| ORD ID | ord-8b3bb53a700c4aa598605a96d7668fee |
| 출처 메모 | uspto-grants-2012_09 |