反应详情

Following the general method as outlined in Intermediate 12, starting from 3-bromo-4-pyridinecarboxaldehyde (Aldrich) and ethyltriphenylphosphonium bromide, the title compound (mixture of cis and trans isomers) was obtained as a colorless liquid after purification by flash column chromatography, eluting with cyclohexane containing increasing amounts of EtOAc.