Isopropyltriphenylphosphonium iodide → HCID 58522086, compound

HRID 2390149Notes

Reaction equation

HRID 2390149 reaction equation
[Br:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[CH:8]=[CH:9][CH2:10]CCC.Br[C:15]1C=NC=CC=1C=O.[I-].C([P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)(C)C>>[Br:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[CH:8]=[C:9]([CH3:10])[CH3:15]

Participants

4

Reactant 3

HCID 2723783Isopropyltriphenylphosphonium iodideHCID 27629973-Bromopyridine-4-carboxaldehydeHCID 670080793-Bromo-4-(hex-1-en-1-yl)pyridine

Product 1

HCID 58522086HCID 58522086, compound

Procedure

Following the general method as outlined in Intermediate 12, starting from 3-bromo-4-pyridinecarboxaldehyde (Aldrich) and isopropyltriphenylphosphonium iodide, the title compound was obtained as a yellow liquid after purification by flash column chromatography, eluting with cyclohexane containing increasing amounts of EtOAc.

Sources & evidence

ORD record
ord-8e4063fddd9b496180018803958ca9ee
Source dataset
uspto-grants-2012_09
Patent number
US08273769B2

Reaction notes

Loading…