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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2390170Generated: October 30, 2026

2-Bromo-6-methylpyridin-3-ol → Tert-butyl 2-[(2-bromo-6-methyl-3-pyridinyl)oxy]acetate

https://huagongshe.com/reaction/2390170

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-6-methylpyridin-3-olHCID 11959101—
Reactanttert-Butyl (2-bromo-4-chlorophenoxy)acetateHCID 49766393—
ProductTert-butyl 2-[(2-bromo-6-methyl-3-pyridinyl)oxy]acetateHCID 5852206379%

Reaction Steps

Following the general method as outlined in Intermediate 1, starting from 2-Bromo-6-methylpyridin-3-ol (Activate Scientific), the title compound was obtained in 79% yield as a yellow liquid after purification by flash column chromatography (silica), eluting with chloroform and methanol (98:2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273769B2
Source datasetuspto-grants-2012_09
ORD IDord-25ade33699ab498f90109234595a8ecc
Source noteuspto-grants-2012_09