Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2390246Generated: October 30, 2026

4-Bromo-2-iodophenol → Tert-butyl (4-bromo-2-iodophenoxy)acetate

https://huagongshe.com/reaction/2390246

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2-iodophenolHCID 10924532—
Reactanttert-Butyl (2-bromo-4-chlorophenoxy)acetateHCID 49766393—
ProductTert-butyl (4-bromo-2-iodophenoxy)acetateHCID 56593849—

Reaction Steps

Following the general method as outlined in Intermediate 1, starting from 4-bromo-2-iodophenol (Intermediate 189), the title compound was obtained as a brown oil after purification by flash column chromatography (silica), eluting with 2% methanol in chloroform.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273769B2
Source datasetuspto-grants-2012_09
ORD IDord-f143b0730e7f4d42a2d6327169e65112
Source noteuspto-grants-2012_09