反应详情

Following the general method as outlined in Intermediate 20, starting from (4-bromo-2-iodo-phenoxy)-acetic acid tert-butyl ester (Intermediate 190) and 1-ethynyl-3-(propane-1-sulfonyl)-benzene (Intermediate 42), the title compound was obtained as a yellow sticky solid after purification by flash column chromatography (silica), eluting with cyclohexane containing increasing amounts of EtOAc.