Diethylamine → HCID 58522021, compound

HRID 2390306Notes

Reaction equation

HRID 2390306 reaction equation
[Br:1][C:2]1[CH:15]=[CH:14][C:5]([C:6]([N:8]([CH2:10][CH2:11]CC)[CH3:9])=[O:7])=[C:4]([S:16]([CH:19]([CH3:21])[CH3:20])(=[O:18])=[O:17])[CH:3]=1.Br[C:23]1C=CC(C(O)=O)=C(S(C(C)C)(=O)=O)C=1.C(NCC)C>>[Br:1][C:2]1[CH:15]=[CH:14][C:5]([C:6]([N:8]([CH2:9][CH3:23])[CH2:10][CH3:11])=[O:7])=[C:4]([S:16]([CH:19]([CH3:21])[CH3:20])(=[O:18])=[O:17])[CH:3]=1

Participants

4

Reactant 3

HCID 8021DiethylamineHCID 56594115HCID 56594115, compound2×HCID 58521909HCID 58521909, compound

Product 1

HCID 58522021HCID 58522021, compoundYield 81%

Procedure

Following the general method as outlined in Intermediate 253, starting from 4-bromo-2-(isopropylsulfonyl)benzoic acid (Intermediate 242) and diethylamine, the title compound was obtained as a pink solid in 81% yield.

Sources & evidence

ORD record
ord-335a4c3fd2ee4462ab3d4b7633f72d2d
Source dataset
uspto-grants-2012_09
Patent number
US08273769B2

Reaction notes

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