反应详情

Following the general method as outlined in Intermediate 183, starting from 2-bromo-4-chloro-1-(methoxymethoxy)benzene (Intermediate 265) and 2-ethynyl-1-methyl-4-(propane-1-sulfonyl)-benzene (Intermediate 40), the title compound was obtained as a white solid in 70% yield after purification by flash column chromatography (silica), eluting with cyclohexane containing increasing amounts of EtOAc.