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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2390729Generated: October 29, 2026

1-Methyl-1H-indole-2-carbonyl chloride → N-[4-(4-amino-7-{[3-(4-hydroxypiperidin-1-yl)propanoyl]amino}thieno[3,2-c]pyridin-3-yl)-2-methoxyphenyl]-1-methyl-1H-indole-2-carboxamide

https://huagongshe.com/reaction/2390729

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-1H-indole-2-carbonyl chlorideHCID 12303314—
ReactantHCID 18451406HCID 18451406—
ProductN-[4-(4-amino-7-{[3-(4-hydroxypiperidin-1-yl)propanoyl]amino}thieno[3,2-c]pyridin-3-yl)-2-methoxyphenyl]-1-methyl-1H-indole-2-carboxamideHCID 18451117—

Reaction Steps

The title compound was prepared using 1-methyl-1H-indole-2-carbonyl chloride, N-[4-Amino-3-(4-amino-3-methoxyphenyl)-thieno[3,2-c]pyridin-7-yl]-3-(4-hydroxy-piperidin-1-yl)propionamide, and the procedure described in General Procedure F. m/z (M+H)+599.4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273736B2
Source datasetuspto-grants-2012_09
ORD IDord-30d634b1269a4a9fb64565bbf3761110
Source noteuspto-grants-2012_09