HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2,6-Dimethoxypyridin-3-yl)boronic acid → 6-Methoxypyridin-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2,6-Dimethoxypyridin-3-yl)boronic acid | HCID 2762707 | — |
| Reactant | 5-Fluoro-2-methoxypyridine-3-boronic acid | HCID 44717691 | — |
| Product | 6-Methoxypyridin-2-ol | HCID 12678724 | — |
Reaction Steps
I-236 was prepared analogously except in step 4, 5-fluoro-2-methoxy-pyridin-3-yl boronic acid was replaced with 2,6-dimethoxy-pyridin-3-yl boronic acid. The crude material was purified by trituration in 10% methanol in ethyl acetate (10 mL). The solid was filtered and dried to give the 6-methoxy pyridone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273773B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-94927ff9e27d4e1190ba42b157379e8b |
| Source note | uspto-grants-2012_09 |