HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 239096Generated: October 29, 2026
Thiourea → 5,6,7,8-tetrahydro-4H-Thiazolo[4,5-d]azepin-2-amine hydrobromide
https://huagongshe.com/reaction/239096
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | 5-Bromoazepan-4-one hydrobromide | HCID 22620766 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5,6,7,8-tetrahydro-4H-Thiazolo[4,5-d]azepin-2-amine hydrobromide | HCID 86686029 | 103.7% |
Reaction Steps
1.44 g thiourea was added to 4 g 5-bromo-azepan-4-one hydrobromide in 50 mL ethanol and stirred 3 h at 80° C. and over the weekend at RT. The precipitate was filtered and dried to yield 3.8 g of the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08642774B2 |
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| Source dataset | uspto-grants-2014_02 |
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| ORD ID | ord-39df6a185c8547c2b9c3bdcbe6a8d702 |
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| Source note | uspto-grants-2014_02 |
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