HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-2-butanone → HCID 86686485, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-2-butanone | HCID 20026 | — |
| Reactant | 1-Benzylpiperidine-4-carboxamide | HCID 783156 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86686485 | HCID 86686485 | — |
Reaction Steps
7 g 1-benzyl-piperidine-4-carboxylic acid amide and 13 mL 3-chlorobutan-2-on were stirred 6 h at 180° C. under microwave conditions. The mixture was diluted in methanol and n-methylpyridinone and purified by HPLC to give 1.48 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642774B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-b70e4ae06675439e9ff5076016b0480d |
| Source note | uspto-grants-2014_02 |