HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-methyl-1H-1,2,3-triazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl 1-methyl-1H-1,2,3-triazole-4-carboxylate | HCID 21278002 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-methyl-1H-1,2,3-triazole-4-carboxylic acid | HCID 21766412 | 50% |
Reaction Steps
Using ethyl 1-methyl-1H-1,2,3-triazole-4-carboxylate (1.48 g, 9.54 mmol), methanol (22 mL), 1N sodium hydroxide (15 mL) and 1N hydrochloric acid (15 mL) as starting materials and in the same manner as in Reference Example 12, the title compound (605 mg, 50%) was obtained as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273741B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-af1c90b250204a2e9a71d79db743b366 |
| Source note | uspto-grants-2012_09 |