HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 3-(2-methoxyethoxy)-1-methyl-1H-pyrazole-5-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | methyl 3-(2-methoxyethoxy)-1-methyl-1H-pyrazole-5-carboxylate | HCID 57441051 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-(2-methoxyethoxy)-1-methyl-1H-pyrazole-5-carboxylic acid | HCID 57441052 | 96.4% |
Reaction Steps
Using methyl 3-(2-methoxyethoxy)-1-methyl-1H-pyrazole-5-carboxylate (3.03 g, 14.1 mmol), methanol (15 mL) and 8N aqueous sodium hydroxide solution (3.00 mL), and in the same manner as in Reference Example 58, the title compound (2.72 g, yield 96%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273741B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-501d504e23c642d88c559ad4e0314105 |
| Source note | uspto-grants-2012_09 |