反应详情

温度

50 °C

2.5 g palladium charcoal was added to 4.6 g 1-(1-benzyl-4-methyl-piperidin-4-yl)-3-methyl-1,3-dihydro-benzoimidazol-2-one in 100 mL methanol. The reaction was stirred 3 h at 50° C. and 30 bar under hydrogen. The reaction was filtered and evaporated to yields 3 g of the desired product. (M+H)+: 246

1. filtrationThe reaction was filtered
2. customevaporated