Sodium borohydride → Benzyl-(2,2-dimethoxy-1-methyl-ethyl)-amine

Participants

Reaction Steps

3.95 g sodium borohydride was added to 18.9 g benzyl-(2,2-dimethoxy-1-methyl-ethylidene)-amine in 100 mL methanol at 0-5° C. The reaction was stirred over night at RT. The solvent was removed, dissolved in toluol and washed with water and saturated ammoniumchloride solution. The organic layer was evaporated and the residue was purified by column chromatographie on silica gel (cyclohexane/ethylacetate) to give 10.7 g of the desired product.

Provenance & Evidence