HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18321017, compound → HCID 18321195, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18321017 | HCID 18321017 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Product | HCID 18321195 | HCID 18321195 | — |
Reaction Steps
100 mg (3-(1-benzyl-piperidin-4-yl)-5-chloro-3,4-dihydro-1H-quinazolin-2-one and 15 mg Raney nickel were stirred for 12 h at RT in a hydrogen atmosphere (30 psi). The reaction was filtered and the filtrate was evaporated to give 67 mg of the desired product. (M+H)+: 266
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642774B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-159903198b7f4a72b6cac0c7e812f6bf |
| Source note | uspto-grants-2014_02 |