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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2391571Generated: October 30, 2026

Ammonia → HCID 25152659, compound

https://huagongshe.com/reaction/2391571

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantHCID 68766494HCID 68766494—
SolventMethanolHCID 887—
ProductHCID 25152659HCID 25152659—

Reaction Steps

In a similar manner as described for example 1, 246 mg of methyl 5-{6-[(2-methoxyethyl)carbamoyl]-1H-imidazo[4,5-c]pyridin-1-yl}-3-{[2-(trifluoromethyl)benzyl]oxy}thiophene-2-carboxylate (compound B8) and 40 ml of a saturated solution of ammonia in methanol give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273890B2
Source datasetuspto-grants-2012_09
ORD IDord-3eb920ea51dd45f0a68bafbd80feb3d3
Source noteuspto-grants-2012_09