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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2391588Generated: October 31, 2026

Ammonia → HCID 25153285, compound

https://huagongshe.com/reaction/2391588

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantHCID 68769258HCID 68769258—
SolventMethanolHCID 887—
ProductHCID 25153285HCID 25153285—

Reaction Steps

In a similar manner as described for example 20, 4.41 g of methyl 5-(3H-imidazo[4,5-b]pyridin-3-yl)-3-{[2-(trifluoromethyl)benzyl]oxy}thiophene-2-carboxylate (compound B5b) and 400 ml of a saturated solution of ammonia in methanol yield the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273890B2
Source datasetuspto-grants-2012_09
ORD IDord-cd5c66f7ff6346049432a6580ac2b545
Source noteuspto-grants-2012_09