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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2391638Generated: October 30, 2026

Cyclopropylamine → HCID 68768682, compound

https://huagongshe.com/reaction/2391638

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropylamineHCID 69828—
Reactant[3-(5-carbamoyl-4-{(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy}-2-thienyl)-3H-imidazo[4,5-c]pyridin-6-yl]methyl methanesulfonateHCID 86647106—
SolventDichloromethaneHCID 6344—
ProductHCID 68768682HCID 68768682—

Reaction Steps

In a similar manner as described for example 58, 289 mg of crude [3-(5-carbamoyl-4-{(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy}-2-thienyl)-3H-imidazo[4,5-c]pyridin-6-yl]methyl methanesulfonate (example 49, step 1) and 0.35 ml cyclopropylamine in 7 ml dichloromethane yield the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273890B2
Source datasetuspto-grants-2012_09
ORD IDord-e5b97dc1b4b241b2ae7111b736299ad8
Source noteuspto-grants-2012_09