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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2391647Generated: November 1, 2026

1-(Morpholinocarbonylmethyl)piperazine → HCID 68766306, compound

https://huagongshe.com/reaction/2391647

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Morpholinocarbonylmethyl)piperazineHCID 100622—
Reactant[1-(5-carbamoyl-4-{(1R)-1-[2-(trifluoro-methyl)phenyl]ethoxy}-2-thienyl)-1H-imidazo[4,5-c]pyridin-6-yl]methyl methanesulfonateHCID 86647102—
SolventDichloromethaneHCID 6344—
ProductHCID 68766306HCID 68766306—

Reaction Steps

In a similar manner as described for example 58, 108 mg of [1-(5-carbamoyl-4-{(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy}-2-thienyl)-1H-imidazo[4,5-c]pyridin-6-yl]methyl methanesulfonate and 213.3 mg of 4-(piperazin-1-ylacetyl)morpholine in 2.5 ml dichloromethane give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273890B2
Source datasetuspto-grants-2012_09
ORD IDord-4a8c534d270246d7b15428456c5f81cd
Source noteuspto-grants-2012_09