Hydrochloric Acid → 3-phenyl-6,7,8,9-tetrahydro-5H-1,2,7-triaza-benzocycloheptene dihydrochloride

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Reaction Steps

40 mL hydrogen chloride in dioxane was added to 5.5 g 3-phenyl-5,6,8,9-tetrahydro-1,2,7-triaza-benzocycloheptene-7-carboxylic acid tert-butyl ester in 40 mL dioxane at 5° C. The reaction was stirred over night. The solvent was removed and co-evaporated with ethyl acetate to yield 3.7 g of the desired product. Rt: 4.09 min (method AE), (M+H)+: 226

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