HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Azepan-4-one hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-tert-Butyl 4-ethyl 5-oxoazepane-1,4-dicarboxylate | HCID 4436570 | — |
| Product | Azepan-4-one hydrochloride | HCID 22021728 | — |
Reaction Steps
20 g 5-Oxo-azepane-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester was stirred over night at 110° C. in 200 mL 6 M hydrochloric acid. The reaction was concentrated to yield 11 g of the desired product. Rf: 0.20 (dichlormethane/methanol=9/1), (M+H)+=114
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642774B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-fe137c72a2694cdaa52050491cbc655d |
| Source note | uspto-grants-2014_02 |