2-Morpholinoethylamine → HCID 178523408, compound

Participants

Reaction Steps

2.0 g of methyl-1H-imidazo[4,5-c]pyridine-6-carboxylate (example D2), 22.1 g of 2-morpholin-4-ylethanamine and 70 ml methanol were placed in an autoclave for 2 h at 140° C. The methanol and 2-morpholin-4-ylethanamine were distilled off the reaction mixture under reduced pressure and the residue was purified by flash chromatography. After crystallization from ethyl acetate/n-hexane the title compound was obtained.

Provenance & Evidence