HRID2392636

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc(N)cc1N(CCN(C)C)C(=O)OC(C)(C)C

HCID10828698

未命名化合物

结构：Cc1nc(-c2ccc(-c3ccc(C(=O)O)cc3)c(C)c2)no1

HCID11130168

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(NC(=O)c2ccc(-c3ccc(-c4noc(C)n4)cc3C)cc2)cc1N(CCN(C)C)C(=O)OC(C)(C)C

HCID10674839

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from N,N-dimethyl-N'-t-butyloxycarbonyl-N'-(5-amino-2-methoxyphenyl)ethylenediamine (D21, 0.37 g, 0.0012 mole) and 2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl) biphenyl-4-carboxylic acid (EP 0533268 A1) (0.34 g, 0.0012 mol) using the method of Example 1 (0.40 g, 57%)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9b1db326f46a4597a0e19a845179ca7e
来源数据集: uspto-grants-1998_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05801170
来源说明: uspto-grants-1998_09

反应 SMILES

[CH3:1][N:2]([CH3:22])[CH2:3][CH2:4][N:5]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[C:6]1[CH:11]=[C:10]([NH2:12])[CH:9]=[CH:8][C:7]=1[O:13][CH3:14].[CH3:23][C:24]1[CH:29]=[C:28]([C:30]2[N:34]=[C:33]([CH3:35])[O:32][N:31]=2)[CH:27]=[CH:26][C:25]=1[C:36]1[CH:41]=[CH:40][C:39]([C:42](O)=[O:43])=[CH:38][CH:37]=1>>[CH3:22][N:2]([CH3:1])[CH2:3][CH2:4][N:5]([C:6]1[CH:11]=[C:10]([NH:12][C:42]([C:39]2[CH:38]=[CH:37][C:36]([C:25]3[CH:26]=[CH:27][C:28]([C:30]4[N:34]=[C:33]([CH3:35])[O:32][N:31]=4)=[CH:29][C:24]=3[CH3:23])=[CH:41][CH:40]=2)=[O:43])[CH:9]=[CH:8][C:7]=1[O:13][CH3:14])[C:15]([O:17][C:18]([CH3:19])([CH3:21])[CH3:20])=[O:16]