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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2392655Generated: October 25, 2026

2-Chloro-5-nitrophenol → 4'-(5-Methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxylic acid

https://huagongshe.com/reaction/2392655

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-nitrophenolHCID 69264—
Reactant4-Carboxyphenylboronic AcidHCID 312183—
Reactant3-(4-Bromophenyl)-5-methyl-1,2,4-oxadiazoleHCID 823560—
Product4'-(5-Methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxylic acidHCID 21833757—

Reaction Steps

The title compound was prepared from 4-(5-methyl-1,2,4-oxadiazol-3-yl)bromobenzene (0.58 g) and 4-boronobenzoic acid (0.4 g) as described in Description 15 as a white solid (0.64 g, 97%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05801170
Source datasetuspto-grants-1998_09
ORD IDord-da702538d4184897a497a7d16f345759
Source noteuspto-grants-1998_09