1-(4-Nitrophenyl)-1H-1,2,4-triazole → 4-(1,2,4-Triazol-1-yl)aniline

HRID 2392671Notes

Reaction equation

HRID 2392671 reaction equation
[N:1]1([C:6]2[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[CH:8][CH:7]=2)[CH:5]=[N:4][CH:3]=[N:2]1>C(O)C.[Pd]>[N:1]1([C:6]2[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][CH:7]=2)[CH:5]=[N:4][CH:3]=[N:2]1

Participants

4

Reactant 1

HCID 110953981-(4-Nitrophenyl)-1H-1,2,4-triazole

Product 1

HCID 7358264-(1,2,4-Triazol-1-yl)anilineYield 87%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

4-(1,2,4-Triazol-1-yl)nitrobenzene (0.5 g, 3 mmol) and Pd/C (500 mg) in ethanol (50 ml) were hydrogenated at rtp for 3 days. The suspension was filtered through celite, evaporated under reduced pressure to afford a white solid (418 mg, 87%).

Workup

  1. filtrationThe suspension was filtered through celite
  2. customevaporated under reduced pressure

Sources & evidence

ORD record
ord-464669df42a34bb8ac4435d69214ab86
Source dataset
uspto-grants-1998_09
Patent number
US05801170

Reaction notes

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