Water → 2-(4-Nitrophenyl)-2H-tetrazole

HRID 2392674Notes

Reaction equation

HRID 2392674 reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=1.[NH:11]1[CH:15]=[N:14][N:13]=[N:12]1.C(=O)([O-])[O-].[K+].[K+].O>CS(C)=O>[N:11]1[N:12]([C:2]2[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=2)[N:13]=[N:14][CH:15]=1

Participants

6

Reactant 4

HCID 962WaterHCID 9590p-FluoronitrobenzeneHCID 11430Potassium CarbonateHCID 178418441HCID 178418441, compound

Product 1

HCID 5338832-(4-Nitrophenyl)-2H-tetrazoleYield 31.1%

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Conditions

Temperature
90 °C

Procedure

4-Fluoronitrobenzene (2 g, 0.014 mol), tetrazole (1 g, 0.014 mol), potassium carbonate (1.96 g, 0.014 mol) were dissolved in DMSO (50 ml) and stirred at 90° C. for 24 h under dry conditions. The yellow suspension was poured into water (150 ml), the resulting yellow solid filtered of and dried in vacuo to afford the title compound (831 mg, 31%).

Workup

  1. filtrationthe resulting yellow solid filtered of and
  2. customdried in vacuo

Sources & evidence

ORD record
ord-0cd414fbc8954a53b521769390788781
Source dataset
uspto-grants-1998_09
Patent number
US05801170

Reaction notes

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