2-(4-Nitrophenyl)-2H-tetrazole → 4-(2H-1,2,3,4-tetrazol-2-yl)aniline

HRID 2392675Notes

Reaction equation

HRID 2392675 reaction equation
[N:1]1[N:2]([C:6]2[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[CH:8][CH:7]=2)[N:3]=[N:4][CH:5]=1>C(O)C.[Pd]>[N:1]1[N:2]([C:6]2[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][CH:7]=2)[N:3]=[N:4][CH:5]=1

Participants

4

Reactant 1

HCID 5338832-(4-Nitrophenyl)-2H-tetrazole

Product 1

HCID 5716394-(2H-1,2,3,4-tetrazol-2-yl)anilineYield 114%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

4-(Tetrazol-2-yl)nitrobenzene (0.83 g, 4.3 mmol) and Pd/C (300 mg) in ethanol (50 ml) were hydrogenated at rtp for 3 days. The suspension was filtered through celite, evaporated under reduced pressure to afford a white solid (790 mg, 100%).

Workup

  1. filtrationThe suspension was filtered through celite
  2. customevaporated under reduced pressure

Sources & evidence

ORD record
ord-73dc5d7ccca44ef1825e112fff6079eb
Source dataset
uspto-grants-1998_09
Patent number
US05801170

Reaction notes

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