1-(3-Methyl-4-nitrophenyl)-1,2,4-triazole → 2-Methyl-4-[1,2,4]triazol-1-yl-phenylamine

HRID 2392678Notes

Reaction equation

HRID 2392678 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH:12]=[N:11][CH:10]=[N:9]2)[CH:5]=[CH:4][C:3]=1[N+:13]([O-])=O>C(O)C.[Pd]>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH:12]=[N:11][CH:10]=[N:9]2)[CH:5]=[CH:4][C:3]=1[NH2:13]

Participants

4

Reactant 1

HCID 144502481-(3-Methyl-4-nitrophenyl)-1,2,4-triazole

Product 1

HCID 144502622-Methyl-4-[1,2,4]triazol-1-yl-phenylamineYield 100%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

2-Methyl-4-(1,2,4-Triazol-1-yl)nitrobenzene (1.0 g, 4.9 mmol) and Pd/C (200 mg) in ethanol (50 ml) were hydrogenated at rtp for 3 days. The suspension was filtered through celite, evaporated under reduced pressure to afford a white solid (850 mg, 100%).

Workup

  1. filtrationThe suspension was filtered through celite
  2. customevaporated under reduced pressure

Sources & evidence

ORD record
ord-3f9db7cc5dc84c3a98acce919db0185d
Source dataset
uspto-grants-1998_09
Patent number
US05801170

Reaction notes

Loading…