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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2392680Generated: October 30, 2026

4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzoic Acid → N-[3-(2-Diisopropylaminoethoxy)-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxamide

https://huagongshe.com/reaction/2392680

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzoic AcidHCID 11130168—
Reactant3-(2-Diisopropylaminoethoxy)-4-methoxyanilineHCID 11357613—
ProductN-[3-(2-Diisopropylaminoethoxy)-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxamideHCID 18672736—

Reaction Steps

The title compound was prepared from 2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxylic acid (EP 0533268 A1) and 3-(2-diisopropylaminoethoxy)-4-methoxyaniline (D4) following a procedure similar to that described in Example 1 (27%) mp 130°-131° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05801170
Source datasetuspto-grants-1998_09
ORD IDord-6c1a9fe6c7df48c4b3fb8dd28175762d
Source noteuspto-grants-1998_09