4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzoic Acid → N-[3-(2-Dimethylaminoethylthio)-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxamide

Participants

Role	Name	HCID	Charge
Reactant	4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzoic Acid	HCID 11130168	—
Reactant	4-Amino-2-(2-dimethylaminoethylthio)anisole	HCID 18980101	—
Product	N-[3-(2-Dimethylaminoethylthio)-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxamide	HCID 18980133	—

Reaction Steps

The title compound was prepared from 2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxylic acid (EP 0533268 A1) and 4-amino-2-(2-dimethylaminoethylthio)anisole (D48) using a similar procedure to Example 1 (50%) mp 138°-9° C.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05801170
Source dataset	uspto-grants-1998_09
ORD ID	ord-dbf53c67b0e647f5847c60a2595a18b1
Source note	uspto-grants-1998_09