Potassium Bromide → HCID 178518638, compound

HRID 2392718Notes

Reaction equation

HRID 2392718 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([NH:9][C:10](=[O:19])[CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[C:14](C)[CH:13]=2)=[C:4]([N+:20]([O-:22])=O)[CH:3]=1.ClC1C=C2C(=CC=1Cl)NC(=[O:35])C(C1C=CC(OC)=CC=1)=[N+]2[O-].[K+].[Br-]>CCO>[Cl:1][C:2]1[CH:3]=[C:4]2[C:5](=[CH:6][C:7]=1[Cl:8])[NH:9][C:10](=[O:19])[C:11]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[OH:35])=[N+:20]2[O-:22]

Participants

5

Reactant 3

HCID 253877Potassium BromideHCID 18980361HCID 18980361, compoundHCID 67729897HCID 67729897, compound

Product 1

HCID 178518638HCID 178518638, compoundYield 30%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The title compound was prepared according to the general procedure of Example 15, except that nitrone 133 is substituted for nitrone 128. Yield: 30%; mp 266°-268° C. (from EtOH); IR (KBr) 3440, 3218, 3102, 2929, 1674, 1619, 1470, 1348, 1143 and 1112 cm-1 ; 1H NMR (in DMSO-d6) δ6.86 (m, 2H), 7.25 (m, 2H), 7.53 (s, 1H), 8.28 (s, 1H), 9.41 (br.s, 1H, O--H), 12.57 (br.s, 1H, N--H); HPLC: 99%; HRMS Calcd for C14H8N2O3Cl2 : 321.9912.

Sources & evidence

ORD record
ord-9965b0fa5e404648829bc413f85a624f
Source dataset
uspto-grants-1998_09
Patent number
US05801183

Reaction notes

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