Piperazine → Piperazinium N,N'-diacetyl-L-cystinate

HRID 2393056Notes

Reaction equation

HRID 2393056 reaction equation
[C:1]([NH:4][C@H:5]([C:18]([OH:20])=[O:19])[CH2:6][S:7][S:8][CH2:9][C@H:10]([NH:14][C:15](=[O:17])[CH3:16])[C:11]([OH:13])=[O:12])(=[O:3])[CH3:2].[NH:21]1[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]1>O>[NH2+:21]1[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]1.[C:15]([NH:14][C@H:10]([C:11]([O-:13])=[O:12])[CH2:9][S:8][S:7][CH2:6][C@H:5]([NH:4][C:1](=[O:3])[CH3:2])[C:18]([O-:20])=[O:19])(=[O:17])[CH3:16]

Participants

4

Reactant 2

HCID 4837PiperazineHCID 6995101N,N'-Diacetyl-L-cystine

Product 1

HCID 131718840Piperazinium N,N'-diacetyl-L-cystinate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To N,N'-diacetyl-L-cystine (4.60 mmole, 1.49 g) dissolved in 5 mL of water was added piperazine (4.60 mmole, 0.90 g). To the solution was added enough isopropanole to cause formation of an oil, which slowly solidifies. The salt was isolated and dried.

Workup

  1. additionTo the solution was added enough isopropanole
  2. customThe salt was isolated
  3. customdried

Sources & evidence

ORD record
ord-9bec7ad55db5403f8869e3278590523f
Source dataset
uspto-grants-1998_09
Patent number
US05804582

Reaction notes

Loading…