HCID 18978989, compound → HCID 178440622, compound

Participants

Reaction Steps

A solution of 0.2 g of 5-butyl-3-methyl-6-[[2'-[N-triphenylmethyl-(1H-tetrazol-5-yl)]biphenyl-4-yl]methyl]imidazo[1,2-a]pyrimidin-2,7-dione in 6 ml of AcOH and 2 ml of H2O is stirred at room temperature for 5 h, then is evaporated under reduced pressure. The residue is taken up into H2O, adjusted to pH 8 with diluted NaOH and extracted with AcOet. The aqueous phase is acidified to pH 5 with AcOH, to separate a solid which is filtered off and washed with H2O, to obtain 0.1 g of a white solid (80% yield, m.p=192°-194° C. dec.).

Provenance & Evidence