Hydrochloric Acid → HCID 18974714, compound

Participants

Reaction Steps

The urea (7.67) (100 mg, 0.27 mmol) was added to a stirred solution of sodium hydroxide (1M, 5 ml). After 0.5 h the reaction was complete by TLC examination. The reaction mixture was neutralised to pH 2 with 1M HCl, causing the urea to precipitate. The precipitate was collected by filtration, washed, dried, and recrystallised from dioxan to give the title compound 7.65 as a yellow powder (82 mg, 91%).

Provenance & Evidence