Formic Acid → HCID 53896014, compound

HRID 2393257Notes

Reaction equation

HRID 2393257 reaction equation
[CH3:1][C@@:2]12[C:10](=[O:11])[CH2:9][CH2:8][C@H:7]1[C@@H:6]1[CH2:12][CH:13]=[C:14]3[CH2:19][C@@H:18]([OH:20])[CH2:17][CH2:16][C@:15]3([CH3:21])[C@H:5]1[CH2:4][CH2:3]2.O.[CH:23](O)=[O:24]>>[CH:23]([O:20][C@H:18]1[CH2:17][CH2:16][C@@:15]2([CH3:21])[C:14](=[CH:13][CH2:12][C@@H:6]3[C@@H:5]2[CH2:4][CH2:3][C@@:2]2([CH3:1])[C@H:7]3[CH2:8][CH2:9][C:10]2=[O:11])[CH2:19]1)=[O:24]

Participants

4

Reactant 3

HCID 284Formic AcidHCID 962WaterHCID 5881Dehydroepiandrosterone

Product 1

HCID 53896014HCID 53896014, compound

Conditions

Temperature
60 °C

Procedure

Following the procedure described by Ringold (H. J. Ringold, et al., J. Am. Chem. Soc. 78, 816, 1956), dehydroepiandrosterone (2.88 g, 10 mmol) dissolved in 85% formic acid (100 mL) is heated at 60 ° C. for 1 h. After cooling, the mixture is poured into iced water and after 16 h, crystals are filtered and dried in vacuo.

Workup

  1. temperatureAfter cooling
  2. filtrationcrystals are filtered
  3. customdried in vacuo

Sources & evidence

ORD record
ord-fc70f90776f14c4292717dcf9c57c5c4
Source dataset
uspto-grants-1998_09
Patent number
US05807849

Reaction notes

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