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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2393653Generated: October 25, 2026

Acetic Anhydride → (R)-N2-Acetyl-N5-[amino(nitroimino)methyl]-N-[(4-hydroxyphenyl)methyl]-ornithinamide

https://huagongshe.com/reaction/2393653

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AnhydrideHCID 7918—
Reactant(R)-N5-[amino(nitroimino)methyl]-N-[(4-hydroxyphenyl)methyl)-ornithinamideHCID 136381090—
SolventAcetic AcidHCID 176—
Product(R)-N2-Acetyl-N5-[amino(nitroimino)methyl]-N-[(4-hydroxyphenyl)methyl]-ornithinamideHCID 136381103—

Reaction Conditions

Temperature50 °C

Reaction Steps

0.3 g (0.925 mMol) of (R)-N5 -[amino(nitroimino)methyl]-N-[(4-hydroxyphenyl)methyl]-ornithinamide were dissolved in 3 ml of glacial acetic acid and after the addition of 3 ml (0.032 Mol) of acetic anhydride the mixture was heated to a reaction temperature of 50° C. for 30 minutes. The product remaining after the volatile components had evaporated off was further processed without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05807875
Source datasetuspto-grants-1998_09
ORD IDord-31ea9a0506fa40a8941c09e0e2b196c5
Source noteuspto-grants-1998_09