Potassium Carbonate → HCID 18976540, compound

Participants

Reaction Conditions

Reaction Steps

13.24 g (116 mmol) 1-methylhydantoin, 19.34 g (140 mmol) waterfree potassium carbonate and 29.2 g (3-bromo-propionaldehyd-dimethylacetal are allowed to react in 90 ml dimethylsulfoxid for 3 hours and 25 minutes at 112°-115° C. The reaction mixture is subsequently cooled to 5° C. and filtered with suction. The filtrate is evaporated in a rotary evaporator and the liquid crude product is purified by fractional distillation in vacuo to give 12.44 g (49.6% of theory) liquid 3-(3,3-dimethoxy-propyl)-1-methyl-imidazolidin-2,4-dione, having a boiling point of 112°-114° C./0.07 mbar.

Provenance & Evidence