Potassium Hydroxide → HCID 10858299, compound

HRID 2393781Notes

Reaction equation

HRID 2393781 reaction equation
[CH3:1][O:2][C:3](=[O:21])[C:4]([CH2:17][C:18]([Cl:20])=[CH2:19])(C(OC)=O)[CH2:5][C:6]([O:8][C:9]([CH3:12])([CH3:11])[CH3:10])=[O:7].[OH-].[K+]>CO.O>[CH3:1][O:2][C:3](=[O:21])[CH:4]([CH2:17][C:18]([Cl:20])=[CH2:19])[CH2:5][C:6]([O:8][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:7]

Participants

5

Reactant 2

HCID 14797Potassium HydroxideHCID 10781998HCID 10781998, compound

Product 1

HCID 10858299HCID 10858299, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

The title compound of Example 2B (1502 g, 4.18 mol) was dissolved in MeOH (2650 mL). While maintaining a temperature of 30° or below for the ensuing mixture, a cold solution of KOH (329 g, 5.85 mol) in H2O (1335 mL) was added dropwise over 20 min. The mixture was stirred vigorously for 24 h.

Workup

  1. temperatureWhile maintaining a temperature of 30° or below for the ensuing mixture

Sources & evidence

ORD record
ord-b4eeca4f23b44f1a9ee2fedf1a691f18
Source dataset
uspto-grants-1998_09
Patent number
US05808085

Reaction notes

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