HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 2-Bromo-4'-(methylsulfonyl)acetophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 4-Methylsulfonylacetophenone | HCID 82529 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Product | 2-Bromo-4'-(methylsulfonyl)acetophenone | HCID 735823 | — |
Reaction Steps
To 4-methanesulfonylacetophenone (480 mg; 2.42 mmol) in 15 mL HOAC was added Br2 (2.42 mmol). The reaction was stirred overnight at r.t. The reaction mixture was carefully poured into NaHCO3 solution and extracted with EtOAC. The reaction yielded a light yellow solid which was used with no further purifiCation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05811425 |
| Source dataset | uspto-grants-1998_09 |
| ORD ID | ord-8407c58680224470bc0ba046e75f170e |
| Source note | uspto-grants-1998_09 |