HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 2-Chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl chloride | HCID 2736708 | — |
| Product | 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylic Acid | HCID 10823150 | 98% |
Reaction Steps
A solution of 2-chloro-4-trifluoromethylpyrimidine-5-carbonyl chloride (2.1 g, 8.6 mmol) in H2O (10 mL) was stirred at 0° C. under N2 for 0.5 h. The resulting solid was filtered and dried to give the title compound (1.91 g, 98% yield); m.p. 232°-234° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05811428 |
| Source dataset | uspto-grants-1998_09 |
| ORD ID | ord-2925b45915284bee82450be7a2476a3e |
| Source note | uspto-grants-1998_09 |