HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → HCID 10846987, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | HCID 10703627 | HCID 10703627 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Chlorine | HCID 24526 | — |
| Product | HCID 10846987 | HCID 10846987 | 75% |
Reaction Steps
The title compound was prepared as described in Example 25, but employing a solution of 2-fluoro-4-trifluoromethylpyrimidine-5-carboxylic acid (1.5 g, 7.1 mmol) and oxalyl chloride (1.0 g, 8 mmol), DMF (2 drops) in CH2 Cl2 (30 mL) resulted in a 75% yield (1.2 g); 1H NMR (CDCl3) δ 9.42 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05811428 |
| Source dataset | uspto-grants-1998_09 |
| ORD ID | ord-dbae4f97a355460c88eedd0b8243546a |
| Source note | uspto-grants-1998_09 |