2,3-Dihydro-1,4-benzodioxin-2-ylmethyl methanesulfonate → HCID 86753136, compound

HRID 2394427Notes

Reaction equation

HRID 2394427 reaction equation
[NH:1]1[C:9]2[CH:8]=[CH:7][CH:6]=[C:5]([CH:10]=[O:11])[C:4]=2[CH:3]=[CH:2]1.CS(O[CH2:17][CH:18]1[O:23][C:22]2[CH:24]=[CH:25][CH:26]=[CH:27][C:21]=2[O:20][CH2:19]1)(=O)=O>>[O:23]1[C:22]2[CH:24]=[CH:25][CH:26]=[CH:27][C:21]=2[O:20][CH2:19][CH:18]1[CH2:17][N:1]1[C:9]2[CH:8]=[CH:7][CH:6]=[C:5]([CH:10]=[O:11])[C:4]=2[CH:3]=[CH:2]1

Participants

3

Reactant 2

HCID 2634452,3-Dihydro-1,4-benzodioxin-2-ylmethyl methanesulfonateHCID 333703Indole-4-carboxaldehyde

Product 1

HCID 86753136HCID 86753136, compound

Procedure

The same procedures used in Example 1 were repeated except for using 870 mg of indole-4-carbaldehyde and 2-benzodioxanylmethyl methanesulfonate instead of the benzyl bromide used in Example 1 to give 699 mg of 1-(2-benzodioxanylmethyl)indole-4-carbaldehyde as a pale yellow oily substance. The yield thereof was found to be 40%.

Sources & evidence

ORD record
ord-b78744f8511748ce8977d97a4e3fa8dc
Source dataset
uspto-grants-1998_09
Patent number
US05811439

Reaction notes

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