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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2394439Generated: October 28, 2026

Indole-3-Carboxaldehyde → HCID 18973548, compound

https://huagongshe.com/reaction/2394439

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndole-3-CarboxaldehydeHCID 10256—
Reactant2-(Bromomethyl)-1,4-difluorobenzeneHCID 522830—
ProductHCID 18973548HCID 1897354892.6%

Reaction Steps

The same procedures used in Example 1 were repeated except for using 3.06 g of 2,5-difluorobenzyl bromide and 2.00 g of indole-3-carbaldehyde as a starting material to give 3.46 g of 1-(2,5-difluorobenzyl)indole-3-carbaldehyde as pale yellow crystals. The yield thereof was found to be 93%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05811439
Source datasetuspto-grants-1998_09
ORD IDord-c5629619d27e414a94325fd572aafb16
Source noteuspto-grants-1998_09