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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2394458Generated: November 1, 2026

2,2,2-trichloro-N-ethylacetamide → 4-(5-Chloro-2-methoxybenzamidomethyl)-6-(ethylaminocarbonyl-aminosulfonyl)-7-methoxychroman

https://huagongshe.com/reaction/2394458

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2,2-trichloro-N-ethylacetamideHCID 4108671—
Reactant4-(5-Chloro-2-methoxybenzamidomethyl)-6-sulfamoyl-7-methoxychromanHCID 11048464—
Product4-(5-Chloro-2-methoxybenzamidomethyl)-6-(ethylaminocarbonyl-aminosulfonyl)-7-methoxychromanHCID 18973615—

Reaction Steps

4-(5-Chloro-2-methoxybenzamidomethyl)-6-(ethylaminocarbonyl-aminosulfonyl)-7-methoxychroman ##STR32## 4-(5-Chloro-2-methoxybenzamidomethyl)-6-(ethylaminocarbonyl-aminosulfonyl)-7-methoxychroman is synthesized analogously to Example 1 from 4-(5-chloro-2-methoxybenzamidomethyl)-6-sulfamoyl-7-methoxychroman and N-ethyltrichloroacetamide. Melting point: 211°-213° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05811448
Source datasetuspto-grants-1998_09
ORD IDord-3add8c00ce544a3386bfb153a05178fd
Source noteuspto-grants-1998_09