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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2394462Generated: October 29, 2026

Butyl Isothiocyanate → 4-(5-Chloro-2-methoxybenzamidomethyl)-6-(n-butylaminothiocarbonylaminosulfonyl)-7-methoxychroman

https://huagongshe.com/reaction/2394462

Reaction equation

Participants

RoleNameHCIDCharge
ReactantButyl IsothiocyanateHCID 11613—
Reactant4-(5-Chloro-2-methoxybenzamidomethyl)-6-sulfamoyl-7-methoxychromanHCID 11048464—
Product4-(5-Chloro-2-methoxybenzamidomethyl)-6-(n-butylaminothiocarbonylaminosulfonyl)-7-methoxychromanHCID 53910337—

Reaction Steps

4-(5-Chloro-2-methoxybenzamidomethyl)-6-(n-butylaminothiocarbonylaminosulfonyl)-7-methoxychroman is prepared analogously to Example 4 from 4-(5-chloro-2-methoxybenzamidomethyl)-6-sulfamoyl-7-methoxychroman and n-butyl isothiocyanate. Melting point: 167° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05811448
Source datasetuspto-grants-1998_09
ORD IDord-dc77a97af1cc434b865a29bfe2974cd6
Source noteuspto-grants-1998_09