Pyridine → HCID 57260647, compound

HRID 2394485Notes

Reaction equation

HRID 2394485 reaction equation
[C:1](Cl)(=[O:3])[CH3:2].[OH:5][CH2:6][CH2:7][NH:8][N:9]=[CH:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.N1C=CC=CC=1>C(OCC)(=O)C>[C:1]([N:8]([CH2:7][CH2:6][OH:5])[N:9]=[CH:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)(=[O:3])[CH3:2]

Participants

5

Reactant 3

HCID 1049PyridineHCID 6367Acetyl chlorideHCID 70531719HCID 70531719, compound

Product 1

HCID 57260647HCID 57260647, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

0.78 g (10-2 moles) of acetyl chloride is added dropwise to a solution containing 10-2 moles of benzaldehyde (2-hydroxyethyl)hydrazone and 0.79 g (10-2 moles) of anhydrous pyridine in 20 ml of anhydrous ethyl acetate, with stirring in the cold.

Sources & evidence

ORD record
ord-a437acda5bef462c9252215f60668040
Source dataset
uspto-grants-1998_09
Patent number
US05811456

Reaction notes

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